Best Form of Delivering Bioidentical Hormone Therapy

The use of hormone pellets is superior to injections. After placing pellets in clients for over 8 years the comparison to injections are superior.

The procedure is safe and performed in the office under local anesthesia.

The chief complaints of BHRT administration with creams and gels are daily administration and a high likelihood of transferring hormones to spouses, children, pets, goldfish and other assorted lovers.  Creams and gels take up to eight weeks to become effective.

Injectables are painful, must be performed once or twice a week, inconvenient for travelers, and subject at times temperature swings.  Injectable, on average, take four weeks to become effective.

Enter BHRT pellet administration.  Modern BHRT pellets release physiologic doses of plant-based, chemically the same as we produce ourselves, hormones, providing optimal therapy.  Pellet therapy is quick, easy, nearly painless following our protocol, cost-effective, and is the quickest onset set of action, four to seven days, of any method of BHRT treatment.

What are Pellets?

BHRT testosterone pellets, are pressed cylinders, smaller than a grain of rice, made specifically for the Regen Medical Center by a PCCA certified compounding pharmacy.  The FDA approved a 75-mg testosterone pellet in 1972.(1)

Pellets provide consistent, healthy hormone level for 4-6 months in men.  In our experience the effects of the pellets may last up to 6 months in men.

Pellets avoid fluctuations in hormone levels, maintain normal ratios of one hormone to another, important for optimal health and disease prevention, and do not increase the risk of blood clots as conventional synthetic hormone replacement therapy does.

Bioidentical pellet therapy is the most popular form of treatment at Regen Medical Center.  We perform four to five pellet procedures daily. First described in 1938, no other form of hormone delivery is as convenient or effective as implant therapy.

Can They Not Hurt?

The procedure does not hurt and takes about 15 minutes to perform. After local anesthesia a small incision is made and the pellets are placed with a trocar beneath  the skin into the fat. Steri-strips applied and cover dressing placed over the surgery site.


Insertion complications parallel any incision based procedure: Minor bleeding or bruising, skin discoloration, infection, and possible pellet extrusion. These are rare. As we use one time only disposable kits, inadequate sterilization of instruments is not an issue.

Testosterone stimulates bone marrow production of red blood cells. Testosterone therapy administered by any method, may cause an elevation in the red blood cells. Though testosterone does not cause a change in clotting factors, if the hemoglobin and hematocrit (blood count) reach a level of 18.5 and 55 respectively, we recommend a blood donation.

Post op concerns are surprisingly few. Theoretically vigorous activity within 48 hours of insertion may cause pellet expulsion. If the patient is immunocompromised or has had a joint replacement we add in a low dose antibiotic.


Bio-identical hormones are safe and effective.

Balanced hormones are the key to health and disease prevention.

What is the onset of action in pellet therapy?

Most patients notice a significant difference with 4-7 days of the implant. Rarely ten days go by without improved symptomatology. Of course, diet, lifestyle, stress reduction, blood sugar balance and total hormone balance are critical for optimal health.

Hormone Monitoring

Every patient undergoes a laboratory evaluation before beginning any hormone therapy.

We repeat labs before each insertion for the first year, then once or twice a year after that.

The Final Word

Bioidentical hormone pellets are a safe and effective. Pellets are convenient, economical, and provide a stable, predictable, hormonal environment. Pellet results are as or more effective than oral, intramuscular or topical hormone administration in regards to bone density, sexual function, mood, cognitive function, lipid profiles, hormone ratios and metabolites.

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